| Tipo de Actividad | Curso/Seminario/Workshop |
| Area(s) de interés | VIDA Biología, Ecología, y Medioambiente
SALU Salud |
| Denominación | Workshop “Proteases at work: cues for understanding neural development and degeneration” |
| Fecha Inicio | 20/10/2014 | Fecha Finalización | 22/10/2014 |
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| Lugar de celebración | Baeza - Jaén - España |
| URL | http://www.unia.es/biomedicine |
| URL para la retransmisión | http://www.unia.es/biomedicine |
Observaciones
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This workshop belongs to the series \"Current Trends in Biomedicine\", organized by the Universidad Internacional de Andalucía (UNIA). The workshop will be held at the \"Campus Antonio Machado\", venue of the UNIA in Baeza (Andalusia, Spain).
More information and application at http://www.unia.es/biomedicine
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Resumen
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Proteolytical processing of membrane bound molecules is emerging as a fundamental mechanism for controlling the strength and timing of cell-to-cell communication, which is at the basis of tissue development and homeostasis. This process acquires particular importance in the context of the brain because its function strongly depends on well-orchestrated interactions among many different cell types. Members of families of metalloproteinases are major effectors of these events. Understanding how proteinases, particularly metalloproteinases, coordinate brain development or how they contribute to brain pathologies when disregulated, requires multi-disciplinary approaches tackling the problem from different perspectives. This workshop will summarize the most recent biochemical and genetic evidence demonstrating that proteases are required for development, function and homeostasis of the CNS, underscoring their relevance in neurodegeneration and discussing whether endogenous or pharmacologica
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