Datos generales

Tipo de ActividadCurso/Seminario/Workshop
Area(s) de interésVIDA Biología, Ecología, y Medioambiente
SALU Salud
DenominaciónWorkshop "Noncoding RNA-mediated metabolic regulation in health and disease"
Fecha Inicio06/11/2017Fecha Finalización08/11/2017

Lugar de celebraciónBaeza - Jaén - España
URLhttp://www.unia.es/biomedicine

Observaciones
This workshop belongs to the series Workshops "Current Trends in Biomedicine", organized by the Universidad Internacional de Andalucía (UNIA).

More information and application at:

http://www.unia.es/biomedicine

Resumen
Work over the last decade has identified the important role of non-coding RNAs in regulating metabolism. Alterations in non-coding RNA expression have been associated to metabolic diseases including dyslipidemia, cardiovascular disease, organ fibrosis, diabetes and obesity. The current reductionist notion distinguishes between long non-coding RNA molecules (lncRNAs, composed by > 200 nucleotides, ribosomal RNAs and others) and small non-coding RNAs, which include transfer, nucleolar and microRNAs (miRNAs). By far, miRNAs are the most well-known and best studied in diverse biomedical contexts even though the availability of next-generation sequencing techniques is allowing to progressively identify and functionally decipher a growing number of lncRNAs. MiRNAs are small non-coding RNA molecules (22 nt) that control gene expression at the posttranscriptional level by affecting mRNA stability and/or translation. LncRNAs regulate gene expression by sequestering endogenous miRNAs...