Tipo de Actividad | Curso/Seminario/Workshop |
Area(s) de interés | VIDA Biología, Ecología, y Medioambiente SALU Salud |
Denominación | Workshop "Noncoding RNA-mediated metabolic regulation in health and disease" |
Fecha Inicio | 06/11/2017 | Fecha Finalización | 08/11/2017 |
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Lugar de celebración | Baeza - Jaén - España |
URL | http://www.unia.es/biomedicine |
Observaciones
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This workshop belongs to the series Workshops "Current Trends in Biomedicine", organized by the Universidad Internacional de Andalucía (UNIA).
More information and application at:
http://www.unia.es/biomedicine
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Resumen
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Work over the last decade has identified the important role of non-coding RNAs in regulating metabolism. Alterations in non-coding RNA expression have been associated to metabolic diseases including dyslipidemia, cardiovascular disease, organ fibrosis, diabetes and obesity. The current reductionist notion distinguishes between long non-coding RNA molecules (lncRNAs, composed by > 200 nucleotides, ribosomal RNAs and others) and small non-coding RNAs, which include transfer, nucleolar and microRNAs (miRNAs). By far, miRNAs are the most well-known and best studied in diverse biomedical contexts even though the availability of next-generation sequencing techniques is allowing to progressively identify and functionally decipher a growing number of lncRNAs. MiRNAs are small non-coding RNA molecules (22 nt) that control gene expression at the posttranscriptional level by affecting mRNA stability and/or translation. LncRNAs regulate gene expression by sequestering endogenous miRNAs...
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